The firstDeadpoolreleased in 2016 owns the record for the biggest R-rated opening at the box office with $132.4M.
That still stands per that analytics group.
Even ifDeadpool & Wolverineisnt as sharp as that projection, its still bound for a fantastic start.

‘Deadpool and Wolverine’Marvel
No pressure, but many have exclaimed that summer isnt starting until the action comedy opens.
3
Disney feels comfortable with the $160M+ range for the Ryan Reynolds-Hugh Jackman team-up with filmmaker Shawn Levy.
3($118.4M)andBlack Panther: Wakanda Forever($181.3M).

The previous twoDeadpoolmovies earned A Cinemascores.